“B\u1ec7nh Alzheimer c\u00f3 l\u00e2y nhi\u1ec5m hay di truy\u1ec1n kh\u00f4ng m\u00e0 trong gia \u0111\u00ecnh m\u1ed9t ng\u01b0\u1eddi b\u1ea1n c\u1ee7a \u00f4ng n\u1ed9i em c\u00f3 \u0111\u1ebfn ba ng\u01b0\u1eddi c\u00f9ng b\u1ecb?”.<\/p>\n\n\n\n
B\u1ec7nh Alzheimer (suy gi\u1ea3m tr\u00ed tu\u1ec7, x\u1ea3y ra \u1edf ng\u01b0\u1eddi c\u00f3 tu\u1ed5i, \u0111\u01b0\u1ee3c Gi\u00e1o s\u01b0 Alois Alzheimer ph\u00e1t hi\u1ec7n v\u00e0o cu\u1ed1i th\u1ec3 k\u1ef7 19) kh\u00f4ng ph\u1ea3i l\u00e0 m\u1ed9t b\u1ec7nh l\u00e2y, m\u00e0 xu\u1ea5t hi\u1ec7n do s\u1ef1 t\u00edch t\u1ee5 protein amyloid-beta trong c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh c\u1ee7a n\u00e3o (b\u00ecnh th\u01b0\u1eddng th\u00ec ch\u1ea5t n\u00e0y b\u1ecb c\u01a1 th\u1ec3 th\u1ea3i ra ngo\u00e0i). Hi\u1ec7n t\u1ea1i, t\u1ef7 l\u1ec7 b\u1ecb b\u1ec7nh n\u00e0y \u1edf \u0111\u1ed9 tu\u1ed5i ngo\u00e0i 65 l\u00e0 10%, ngo\u00e0i 85 l\u00e0 50%.<\/p>\n\n\n\n
L\u00e2u nay, do th\u1ea5y trong m\u1ed9t s\u1ed1 gia \u0111\u00ecnh c\u00f3 nhi\u1ec1u ng\u01b0\u1eddi m\u1eafc b\u1ec7nh n\u00e0y n\u00ean ng\u01b0\u1eddi ta nghi ng\u1edd c\u00f3 y\u1ebfu t\u1ed1 di truy\u1ec1n. Nh\u01b0ng \u0111i\u1ec1u n\u00e0y ch\u01b0a th\u1ec3 kh\u1eb3ng \u0111\u1ecbnh v\u00ec thi\u1ebfu b\u1eb1ng ch\u1ee9ng khoa h\u1ecdc..<\/p>\n\n\n\n
Cu\u1ed1i n\u0103m 1998, khi nghi\u00ean c\u1ee9u c\u00e1c th\u00e0nh vi\u00ean trong m\u1ed9t s\u1ed1 gia \u0111\u00ecnh c\u00f3 \u00edt nh\u1ea5t 2 ng\u01b0\u1eddi b\u1ecb Alzheimer, c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1i B\u1ec7nh vi\u1ec7n Massachusetts (M\u1ef9) \u0111\u00e3 ph\u00e2n l\u1eadp \u0111\u01b0\u1ee3c m\u1ed9t gene, g\u1ecdi l\u00e0 A2M, c\u00f3 vai tr\u00f2 \u0111i\u1ec1u ch\u1ec9nh protein amyloid-beta. Khi gene A2M g\u1eb7p tr\u1ee5c tr\u1eb7c th\u00ec protein n\u00e0y kh\u00f4ng b\u1ecb \u0111\u00e0o th\u1ea3i nh\u01b0 th\u01b0\u1eddng l\u1ec7 m\u00e0 t\u00edch t\u1ee5 trong c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh c\u1ee7a n\u00e3o th\u00e0nh c\u00e1c m\u1ea3ng b\u00e1m. T\u1eeb \u0111\u00f3, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u d\u1ef1 ki\u1ebfn s\u1ebd hi\u1ec7u ch\u1ec9nh \u0111\u01b0\u1ee3c m\u1ed9t lo\u1ea1i thu\u1ed1c b\u1eaft ch\u01b0\u1edbc t\u00e1c \u0111\u1ed9ng t\u00edch c\u1ef1c c\u1ee7a gene A2M l\u00e0nh m\u1ea1nh, ng\u0103n ch\u1eb7n s\u1ef1 t\u00edch t\u1ee5 protein amyloid-b\u00eata.<\/p>\n\n\n\n
Vi\u1ec7n Nghi\u00ean c\u1ee9u L\u00fd sinh Dusseldorf c\u1ee7a \u0110\u1ee9c c\u0169ng t\u00ecm ra \u0111\u01b0\u1ee3c ph\u01b0\u01a1ng c\u00e1ch ph\u00e1t hi\u1ec7n protein amyloid-b\u00eata trong d\u1ecbch n\u00e3o t\u1ee7y, t\u1ea1o thu\u1eadn l\u1ee3i cho vi\u1ec7c ch\u1ea9n \u0111o\u00e1n s\u1edbm b\u1ec7nh Alzheimer. N\u0103m 1999, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u Ailen cho bi\u1ebft h\u1ecd \u0111\u00e3 ch\u1ebf t\u1ea1o th\u00e0nh c\u00f4ng m\u1ed9t vacxin mang t\u00ean AN.1972 c\u00f3 t\u00e1c d\u1ee5ng ng\u0103n ng\u1eeba v\u00e0 ch\u1eefa tr\u1ecb b\u1ec7nh Alzheimer tr\u00ean chu\u1ed9t, hy v\u1ecdng s\u1ebd c\u00f3 th\u1ec3 d\u00f9ng th\u1eed tr\u00ean ng\u01b0\u1eddi.<\/p>\n\n\n\n
Ngo\u00e0i ra, ng\u01b0\u1eddi ta \u0111\u00e3 s\u1ea3n xu\u1ea5t \u0111\u01b0\u1ee3c vacxin \u0111\u1ec3 ti\u00eam ph\u00f2ng b\u1ec7nh Alzheimer. Vacxin n\u00e0y \u0111ang \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi t\u1ea1i M\u1ef9, Ph\u00e1p v\u00e0 nhi\u1ec1u n\u01b0\u1edbc kh\u00e1c trong Li\u00ean minh ch\u00e2u \u00c2u,<\/p>\n","protected":false},"excerpt":{"rendered":"
“B\u1ec7nh Alzheimer c\u00f3 l\u00e2y nhi\u1ec5m hay di truy\u1ec1n kh\u00f4ng m\u00e0 trong gia \u0111\u00ecnh m\u1ed9t ng\u01b0\u1eddi b\u1ea1n c\u1ee7a \u00f4ng n\u1ed9i em c\u00f3 \u0111\u1ebfn ba ng\u01b0\u1eddi c\u00f9ng b\u1ecb?”. B\u1ec7nh Alzheimer (suy gi\u1ea3m tr\u00ed tu\u1ec7, x\u1ea3y ra \u1edf ng\u01b0\u1eddi c\u00f3 tu\u1ed5i, \u0111\u01b0\u1ee3c Gi\u00e1o s\u01b0 Alois Alzheimer ph\u00e1t hi\u1ec7n v\u00e0o cu\u1ed1i th\u1ec3 k\u1ef7 19) kh\u00f4ng ph\u1ea3i l\u00e0 m\u1ed9t b\u1ec7nh […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_disable_autopaging":false},"categories":[21],"tags":[],"class_list":["post-11773","post","type-post","status-publish","format-standard","hentry","category-y-hoc"],"_links":{"self":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/posts\/11773","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/comments?post=11773"}],"version-history":[{"count":0,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/posts\/11773\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/media?parent=11773"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/categories?post=11773"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/tags?post=11773"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}