Khi \u0111\u00e3 nhi\u1ec5m HIV th\u00ec b l\u00e2u sau s\u1ebd c\u00f3 tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng c\u1ee7a b\u1ec7nh AIDS? Y h\u1ecdc th\u1ebf gi\u1edbi \u0111\u00e3 c\u00f3 thu\u1ed1c h\u1eefu hi\u1ec7u ch\u1eefa tr\u1ecb b\u1ec7nh AIDS?<\/p>\n\n\n\n
Sau khi v\u00e0o ng\u01b0\u1eddi – qua \u0111\u01b0\u1eddng t\u00ecnh d\u1ee5c ho\u1eb7c \u0111\u01b0\u1eddng m\u00e1u -, virus HIV th\u00e2m nh\u1eadp c\u00e1c b\u1ea1ch c\u1ea7u CD4 gi\u1eef tr\u1ecdng tr\u00e1ch trong h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3, v\u00e0 li\u00ean ti\u1ebfp t\u1ef1 nh\u00e2n l\u00ean ng\u00e0y c\u00e0ng \u0111\u00f4ng trong lo\u1ea1i b\u1ea1ch c\u1ea7u n\u00e0y.<\/p>\n\n\n\n
Ban \u0111\u1ea7u, c\u01a1 th\u1ec3 ph\u1ea3n \u1ee9ng l\u1ea1i b\u1eb1ng c\u00e1ch t\u0103ng c\u01b0\u1eddng s\u1ea3n xu\u1ea5t b\u1ea1ch c\u1ea7u CD4 nh\u1eb1m b\u00f9 v\u00e0o s\u1ed1 l\u01b0\u1ee3ng b\u1ecb HIV h\u1ee7y ho\u1ea1i, v\u00ec th\u1ebf l\u00fac n\u00e0y HIV v\u1eabn ch\u01b0a l\u00e0m n\u00ean c\u00f4ng chuy\u1ec7n, b\u1ec7nh AIDS ch\u01b0a b\u1ed9c l\u1ed9, s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u CD4 v\u1eabn nh\u01b0 tr\u01b0\u1edbc ho\u1eb7c g\u1ea7n nh\u01b0 tr\u01b0\u1edbc, ch\u1ec9 c\u00f3 th\u1eed m\u00e1u th\u1ea5y HIV d\u01b0\u01a1ng t\u00ednh m\u00e0 th\u00f4i.<\/p>\n\n\n\n
C\u1ee9 th\u1ebf, trong cu\u1ed9c chi\u1ebfn \u0111\u1ea5u kh\u00f4ng c\u00e2n s\u1ee9c \u0111\u00f3, c\u01a1 th\u1ec3 d\u1ea7n d\u00e0 suy y\u1ebfu, m\u1ea5t kh\u1ea3 n\u0103ng s\u1ea3n xu\u1ea5t ti\u1ebfp c\u00e1c b\u1ea1ch c\u1ea7u CD4 \u0111\u1ee7 b\u00f9 \u0111\u1eafp v\u00e0o s\u1ed1 b\u1ea1ch c\u1ea7u CD4 b\u1ecb vurus ti\u00eau di\u1ec7t (ng\u01b0\u1eddi ta th\u1ea5y l\u00fac trong m\u1ed7i 3 ml m\u00e1u ch\u1ec9 c\u00f2n 200 b\u1ea1ch c\u1ea7u CD4, th\u00ec ch\u1ec9 c\u1ea7n 1 vi khu\u1ea9n x\u00e2m nh\u1eadp, c\u01a1 th\u1ec3 s\u1ebd c\u00f3 nguy c\u01a1 b\u1ecb nhi\u1ec5m khu\u1ea9n c\u01a1 h\u1ed9i), b\u1ea5y gi\u1edd hi\u1ec7n t\u01b0\u1ee3ng suy gi\u1ea3m mi\u1ec5n d\u1ecbch c\u1ee7a c\u01a1 th\u1ec3 m\u1edbi bi\u1ec3u hi\u1ec7n ra ngo\u00e0i, \u0111\u00f3 l\u00e0 l\u00fac b\u1ec7nh AIDS c\u00f3 nh\u1eefng tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng \u0111\u1ea7u ti\u00ean: \u0111i \u0111\u00f4i v\u1edbi t\u00ecnh tr\u1ea1ng ng\u00e0y c\u00e0ng suy y\u1ebfu, c\u01a1 th\u1ec3 d\u1ec5 d\u00e0ng b\u1ecb t\u1ea5n c\u00f4ng b\u1edfi b\u1ea5t c\u1ee9 m\u1ea7m b\u1ec7nh g\u00ec (vi khu\u1ea9n, virus, n\u1ea5m) t\u1ea1i b\u1ea5t c\u1ee9 b\u1ed9 ph\u1eadn n\u00e0o, v\u00e0 kh\u00f4ng thu\u1ed1c kh\u00e1ng sinh n\u00e0o c\u00f3 th\u1ec3 tr\u1ee3 gi\u00fap \u0111\u1ec3 thanh to\u00e1n h\u1ebft \u0111\u01b0\u1ee3c, cu\u1ed1i c\u00f9ng d\u1eabn \u0111\u1ebfn c\u00e1i ch\u1ebft.<\/p>\n\n\n\n
Th\u1eddi gian im l\u1eb7ng n\u00f3i tr\u00ean c\u1ee7a HIV t\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 l\u00e2y nhi\u1ec5m, s\u1ee9c \u0111\u1ec1 kh\u00e1ng c\u1ee7a t\u1eebng ng\u01b0\u1eddi, v\u00e0o th\u1eddi c\u01a1 s\u1eed d\u1ee5ng thu\u1ed1c v\u00e0 c\u00f4ng hi\u1ec7u c\u1ee7a thu\u1ed1c d\u00f9ng, v\u00e0o c\u1ea3 tinh th\u1ea7n c\u1ee7a b\u1ec7nh nh\u00e2n, c\u00f3 th\u1ec3 t\u1eeb 1-5 n\u0103m \u0111\u1ebfn 10-15 n\u0103m, v\u00e0 trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p hy h\u1eefu c\u00f3 th\u1ec3 d\u00e0i h\u01a1n ho\u1eb7c tho\u00e1t kh\u1ecfi b\u1ec7nh AIDS b\u1ed9c ph\u00e1t, HIV tr\u1edf l\u1ea1i \u00e2m t\u00ednh trong m\u00e1u.<\/p>\n\n\n\n
V\u1ec1 \u0111i\u1ec1u tr\u1ecb th\u00ec cho t\u1edbi nay ch\u01b0a c\u00f3 lo\u1ea1i thu\u1ed1c n\u00e0o ch\u1eefa d\u1ee9t \u0111\u01b0\u1ee3c b\u1ec7nh, m\u00e0 ch\u1ec9 c\u00f3 t\u00ednh ch\u1ea5t h\u1ed7 tr\u1ee3 c\u01a1 th\u1ec3 ch\u1ed1ng l\u1ea1i cu\u1ed9c t\u1ea5n c\u00f4ng c\u1ee7a virus HIV; gi\u00e1 th\u00e0nh c\u1ee7a thu\u1ed1c c\u00f2n r\u1ea5t cao, ngo\u00e0i t\u1ea7m v\u1edbi c\u1ee7a ng\u01b0\u1eddi ngh\u00e8o.<\/p>\n\n\n\n
\u0110\u1ea7u n\u0103m 1999, m\u1ed9t c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u c\u1ee7a Tr\u01b0\u1eddng \u0111\u1ea1i h\u1ecdc t\u1ed5ng h\u1ee3p Washington t\u1ea1i Saint Louis, Hoa K\u1ef3, \u0111\u00e3 thu \u0111\u01b0\u1ee3c k\u1ebft q\u1ee7a khi s\u1eed d\u1ee5ng m\u1ed9t lo\u1ea1i protein c\u00f3 t\u00e1c d\u1ee5ng ch\u1ec9 ti\u00eau di\u1ec7t c\u00e1c t\u1ebf b\u00e0o b\u1ecb nhi\u1ec5m HIV (l\u00e0m cho HIV kh\u00f4ng c\u00f2n ch\u1ed7 \u0111\u1ec3 sinh s\u00f4i); protein n\u00e0y ch\u1ec9 t\u00e1c \u0111\u1ed9ng khi c\u00f3 m\u1eb7t ch\u1ea5t protease c\u1ee7a HIV l\u00e0 enzyme ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 vi\u1ec7c t\u1ea1o ra c\u00e1c HIV m\u1edbi. Nh\u01b0ng c\u00e1c t\u00e1c gi\u1ea3 c\u1ee7a c\u00f4ng tr\u00ecnh n\u00e0y ch\u01b0a c\u00f3 \u0111i\u1ec1u ki\u1ec7n th\u1ef1c hi\u1ec7n tr\u00ean c\u01a1 th\u1ec3 s\u1ed1ng (in vivo), m\u00e0 ch\u1ec9 m\u1edbi trong \u1ed1ng nghi\u1ec7m (in vitro).<\/p>\n\n\n\n
C\u0169ng v\u00e0o \u0111\u1ea7u n\u0103m 1999, Vi\u1ec7n h\u00e0n l\u00e2m khoa h\u1ecdc qu\u1ed1c gia M\u1ef9 c\u00f4ng b\u1ed1 k\u1ebft q\u1ee7a nghi\u00ean c\u1ee9u cho bi\u1ebft ch\u1ea5t lysozyme trong n\u01b0\u1edbc ti\u1ec3u c\u1ee7a ph\u1ee5 n\u1eef mang thai c\u00f3 kh\u1ea3 n\u0103ng ng\u0103n ch\u1eb7n m\u1ed9t c\u00e1ch h\u1eefu hi\u1ec7u s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a virus HIV (t\u1eeb l\u00e2u ng\u01b0\u1eddi ta \u0111\u00e3 bi\u1ebft lysozyme l\u00e0 m\u1ed9t protein hi\u1ec7n h\u1eefu tr\u00f2ng n\u01b0\u1edbc b\u1ecdt (n\u01b0\u1edbc mi\u1ebfng) v\u00e0 n\u01b0\u1edbc m\u1eaft, c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m tan m\u1ed9t s\u1ed1 t\u1ea1p khu\u1ea9n). Ph\u00e1t hi\u1ec7n n\u00e0y r\u1ea5t quan tr\u1ecdng, m\u1edf ra tri\u1ec3n v\u1ecdng m\u1edbi trong vi\u1ec7c ch\u1ebf t\u1ea1o thu\u1ed1c ch\u1ed1ng virus HIV.<\/p>\n\n\n\n
Tuy nhi\u00ean c\u00f3 m\u1ed9t t\u00ecnh h\u00ecnh \u0111\u00e1ng lo ng\u1ea1i l\u00e0: T\u1ea1i c\u00e1c n\u01b0\u1edbc Ucraina, Belaruxia, m\u1ec7nh danh l\u00e0 HIV-0, g\u00e2y ch\u1ebft nhanh g\u1ea5p \u0111\u00f4i c\u00e1c d\u1ea1ng HIV kh\u00e1c, l\u00e0m ng\u01b0\u1eddi b\u1ec7nh ch\u1ebft ch\u1ec9 sau 3-5 th\u00e1ng, l\u00e2u nh\u1ea5t l\u00e0 1 n\u0103m. C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 kh\u1eb3ng \u0111\u1ecbnh hi\u1ec7n t\u01b0\u1ee3ng \u0111\u1ed9t bi\u1ebfn n\u00e0y c\u1ee7a HIV l\u00e0 do ba n\u01b0\u1edbc n\u00f3i tr\u00ean b\u1ecb nhi\u1ec5m x\u1ea1 sau v\u1ee5 n\u1ed5 nh\u00e0 m\u00e1y \u0111i\u1ec7n nguy\u00ean t\u1eed Tr\u00e9cn\u00f4b\u01b0n n\u0103m 1986.<\/p>\n","protected":false},"excerpt":{"rendered":"
Khi \u0111\u00e3 nhi\u1ec5m HIV th\u00ec b l\u00e2u sau s\u1ebd c\u00f3 tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng c\u1ee7a b\u1ec7nh AIDS? Y h\u1ecdc th\u1ebf gi\u1edbi \u0111\u00e3 c\u00f3 thu\u1ed1c h\u1eefu hi\u1ec7u ch\u1eefa tr\u1ecb b\u1ec7nh AIDS? Sau khi v\u00e0o ng\u01b0\u1eddi – qua \u0111\u01b0\u1eddng t\u00ecnh d\u1ee5c ho\u1eb7c \u0111\u01b0\u1eddng m\u00e1u -, virus HIV th\u00e2m nh\u1eadp c\u00e1c b\u1ea1ch c\u1ea7u CD4 gi\u1eef tr\u1ecdng tr\u00e1ch trong […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_disable_autopaging":false},"categories":[21],"tags":[],"class_list":["post-12743","post","type-post","status-publish","format-standard","hentry","category-y-hoc"],"_links":{"self":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/posts\/12743","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/comments?post=12743"}],"version-history":[{"count":0,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/posts\/12743\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/media?parent=12743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/categories?post=12743"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vietlearn.org\/kien-thuc\/wp-json\/wp\/v2\/tags?post=12743"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}